Dr. Irina Smoliakova

Professor

B.A., 1983, Moscow State University, USSR; Ph.D., 1989, Zelinsky Institute of Organic Chemistry, Russian Academy of Science;1989-91, Research Associate, Zelinsky Institute of Organic Chemistry, Russian Academy of Science; 1991-95, Research Associate, University of Minnesota-Duluth.

 

Our group conducts research at the interface of organic and organometallic chemistry. Currently, we investigate synthesis, structural features and reactivity of cyclopalladated complexes. Cyclopalladated complexes are air‐stable compounds containing a chelate with a covalent Pd–C and dative X–Pd (X = N, P or S) bonds. Particularly, we synthesize new types of chiral cyclopalladated complexes, which may be used as catalysts in asymmetric synthesis and/or reagents for preparing new optically active ligands, e.g. aminophosphines, employed in a number of stereoselective transformations.

The scheme above illustrate stoichiometric and catalytic synthesis of the C,P‐chiral aminophosphine 3 using the optically active cyclopalladated complex 2 either as a catalyst or a reagent. Graduate and undergraduate students working in our group get experience in organic and organometallic synthesis as well as spectroscopic analysis of complex chiral molecules. Former students have been employed in both academia and industry.

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RECENT PUBLICATIONS

1. Han, M.; Smoliakova, I.P.* “Reduction of 2-Arylthio-β-C-D-glucopyranosides with Different Functional Groups in the Lateral Chain.” Synth. Commun. 2011, accepted.

2. Stepanova, V.A.; Dunina, V.V.; Smoliakova, I.P.* “Chemoselectivity Control in the Reaction of a Dinuclear Chloro-Bridged Cyclopalladated Complex with Potassium Diphenylphosphide.” J. Organomet. Chem. 2011, in press, http://dx.doi.org/10.1016/j.jorganchem.2010.10.020

3. Stepanova, V.A.; Kukowski, J.E.; Smoliakova, I.P.* “Cyclopalladation of 2-tert-butyl-4,4-dimethyl-2-oxazoline in solution and on silica gel.” Inorg. Chem. Commun. 2010, 13, 653–655.

4. Smoliakova, I.P.*; Wood, J.L.; Stepanova, V.A.; Mawo, R.Y. “Solvent-free cyclopalladation on silica gel.” J. Organomet. Chem. 2010, 695, 360–364.

5. Stepanova, V.A.; Dunina, V.V.; Smoliakova, I.P.* “Reactions of cyclopalladated complexes with lithium diphenylphosphide.“ Organometallics 2009, 28, 6546–6558.

6. Kubatova, A.*; Lahren, T. J.; Beranek, J.; Smoliakova, I. P.; Braun, A.; Huggins, F. E. “Extractable organic carbon and its differentiation by polarity in diesel exhaust, wood smoke, and urban particulate matter.” Aerosol Science and Technology 2009, 43, 714–729.

7. Mawo, R.Y.; Smoliakova, I.P.* “Cyclopalladation of Enantiopure Oxazolines Having the Prochiral CMe2 Moiety at Position 2 of the Heterocycle.” Polyhedron, 2009, 28, 77–84.

8. Mawo, R.Y.; Johnson, D.M.; Smoliakova, I.P.* “Synthesis of Pd(II) coordination complexes of (S)-4-isobutyl-2-methyl-2-oxazoline and (S)-2-(2,2-dimethylpropyl)-4-isopropyl-2-oxazoline.” Inorg. Chem. Commun. 2008, 11, 1397–1400.

9. Long, E.K.; Smoliakova, I.P.; Honzatko, A.; Picklo, M.J., Sr. “Structural Characterization of α,β-Unsaturated Aldehydes by GC/MS is Dependent upon Ionization Method.” Lipids 2008, 43, 765-774.

10. Mawo, R.Y.; Johnson, D.M.; Wood, J.L.; Smoliakova, I.P.* “Enantiopure Exo and Endo Six-Membered Oxazoline-Derived Palladacycles.” J. Organomet. Chem. 2008, 693, 33-45.

11. Mawo, R.Y.; Mustakim, S.; Young, V. G., Jr.; Hoffmann, M.R.; Smoliakova, I.P.* “Endo-Effect Driven Regioselectivity in the Cyclopalladation of (S)-2-tert-Butyl-4-phenyl-2-oxazoline.” Organometallics 2007, 26, 1801–1810.